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Because the GI system needs to adapt

clean up the inputs and the body's own pathways do the rest

390 More recently, the efficacy of EGFR TKIs has been explored specifically in patients with EGFR-overexpressing ESCC

Unlike genomic and proteomics methods, metabolomics measures endogenous metabolism (metabolomics) as well as perturbations of metabolism caused by environmental factors and pathophysiological processes, offering a snapshot of the physiology of the cell most closely related to the phenotype (90, 91)

Autophagy is normally induced by limitations in adenosine triphosphate (ATP) availability or by a lack of essential nutrients, including glucose and amino acids 12,13,14