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Interestingly, B12 did not affect the intracellular protein levels of IL-1B in the cultures of the SEV group, and, regardless of the treatment, the intracellular protein levels of IL-1B were very low, close to or below the detection limit of the method ( Figure 3F )

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We hypothesized that loading water soluble antioxidants into the hypotonic, gel-forming vehicle could provide therapeutic scavenging of ROS in the posterior segment, a potential therapeutic opportunity for treating RP