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The LPFI has the advantage of contrasting the extent of neuronal injury in the ipsilateral (injured site) and contralateral (non-injured) side of the brain (Hicks et al., 1996)

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Injections tend to be more reliable when the body has trouble absorbing B12 from the gut, such as with pernicious anemia, certain digestive conditions, or after some stomach or intestinal surgeries

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When deficiency is suspected based on clinical features (fatigue, paraesthesia, cognitive changes) or risk factors (vegan diet, gastric surgery, certain medications), serum B12 measurement guides appropriate intervention

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REFERENCES Battie MC, Videman T, Gill K, et al

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The fact that the process of angiogenesis is complicated and involves a network of mechanisms suggests that the tumor microenvironment could mediate resistance to AIs (308)

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