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NAD+ shortage especially affects muscle stem cells, where mitochondrial problems signal stem cell aging, which results in fewer stem cells and less regenerative potential

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In the UK, hydroxocobalamin is the preferred injectable form, with cyanocobalamin rarely used in NHS practice

This can lead to a deficiency over time
This is an important clarification because confusion sometimes arises from the fact that certain other diabetes medicationsparticularly metforminare well-documented to interfere with vitamin B12 absorption
