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Ferroptosis as a Mechanism to Mediate P53 Function in Tumor Radiosensitivity

M., Awad, P., Campisi, J

Di Pierro D, Ciaccio C, Sbardella D, Tundo GR, Bernardini R, Curatolo P, et al

10.1093/ajcn/81.1.326S 549

The IVR domain contains a 3-box motif in its proximal part, which provides an additional CUL3 interaction site [116], and two critical cysteine residues, Cysteine273 (C273) and Cysteine288 (C288), that are important for the repression of NRF2 activity [126]
