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Clinical trial design must account for this heterogeneity, possibly incorporating patient stratification based on imaging, genetic risk factors (e.g., APOE or TREM2 variants), or peripheral cytokine profiles

doi: 10.1038/s41584-020-0451-z 245 Arango DuqueGDescoteauxA

Those darkened cells sit on the surface, making your complexion look dull and uneven

Antifungal agents: polyenes, e.g., amphotericin B, candicidin, dermostatin, filipin, fungichromin, hachimycin, hamycin, lucensomycin, mepartricin, natamycin, nystatin, pecilocin, perimycin

Brain GSH assessment Imaging and voxel selection Brain GSH levels were determined using a Philips Achieva 3.0-T whole-body scanner (Best, The Netherlands) equipped with a 32-channel SENSE phased-array head coil