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However, cortical neurons that also depend much stronger on IIS than on Bdnf-signalling for their survival also activate the PI3K-pAkt branch [117], but LY294002 does not completely attribute for survival upon IIS

[DOI] [PMC free article] [PubMed] Melis JPM, Van Steeg H, Iuijten M

Further research is necessary to delve into the specific regulatory mechanisms of ferroptosis inhibitors and inducers on cell ferroptosis, as well as their effects on autoimmune diseases

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