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Description
The ATP synthesis undergoes a multistep process as follows: post-translational modifications (e.g., oxidative phosphorylation)

For instance, the alexandrite laser is most effective in removing the green-colored tattoo pigment, even though it removes blue and black pigments as well

doi: 10.1002/pro.2858 23 LangFSinghYSalkerMSMaKPandyraAALangPAet al

But in the case of kidney disease, if fixed acids originated from the metabolism are the acidifying factor and kidneys are not capable of adjusting to this daily challenge, the origin of the acidosis comes from the cells and therefore occurs in an intracellular-extracellular fashion (i.e., from the net endogenous acid production)
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