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doi: 10.1172/JCI113570 73
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Treatment of Mmut p.L690Ins/p.L690Ins mice with BCATi actually caused methylmalonic acid levels to increase further in liver relative to the untreated Mmut p.L690Ins/p.L690Ins mice (Figure 8A)
Considered simplistically, four enzymes are involved in the cycle of -oxidation of a long-chain saturated fatty acid as its CoA ester in mitochondria
