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[113] is the formation of 5-OP by deglycinase
Ethylene oxide may, therefore, be considered a potential human mutagen for both somatic and germ cells

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Khapre, R

Clin Pharmacokinet 42:139151 Grnroos M, Chen M, Jahnukainen T, Capitanio A, Aizman RI, Celsi G (2006) Methotrexate induces cell swelling and necrosis in renal tubular cells
