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Glossary Excitatoryinhibitory balance The relative strength of excitatory and inhibitory signalling in a circuit, which together determine circuit excitability and information flow

[DOI] [PubMed] [Google Scholar] [33].Datta SK

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[4] Furthermore, because the reaction catalyzed by the pyruvate dehydrogenase complex, the oxidative decarboxylation of pyruvate to acetyl-CoA, is irreversible , and since animals lack a pathway to convert acetyl-CoA back to pyruvate, acetyl-CoA cannot serve as a glucogenic substrate

Old matrix components are degraded, new proteins are synthesized, and cellular populations reorganize in response to changing physiological demands