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L-Carnitine is a naturally occurring nutrient that plays an essential role in energy production

An open-label, non-randomized trial in 69 patients with either type 1 or type 2 diabetes mellitus found a reduction in the incidence of muscle cramps and an improvement in the quality of life of those prescribed 0.6 g/day of L-carnitine for four months compared to controls (127)

The study included 56 patients (49 women), making it relatively small

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L(-)-Carnitine and its precursor, gamma-butyrobetaine