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Procedural errors, such as improper sample collection, labeling mistakes, or mishandling during transportation, can compromise the integrity of the test results

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Manifestations of histamine release and/or peripheral vasodilation may include pruritus, flushing, red eyes, sweating, and/or orthostatic hypotension

This also suggests that there are no major structural changes at the ATD layer in the desensitized and resting/closed states
