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Friedrich et al., 2013) would be required to definitively identify whether tiling in the RPE is a normal finding of aging, or if it is associated with AMD

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In addition, genetic suppression of phosphoglycerate dehydrogenase (PHGDH), a key enzyme in serine biosynthesis, compromises T cell expansion and antitumor immunity [141,145,146]

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187 , 188 ISB 1342, a bispecific Tcell engager antibody binding to a different CD38 epitope is currently in Phase 1 studies, and has been shown to elicit potent antitumor activity in samples from RRMM patients who have previously received daratumumab