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In all reported GPX families, the tetramer GPX3 eliminates all complex hydroperoxides, circulates in plasma in addition to its roles in cytoplasmic and mitochondria, and is a major ROS scavenger in plasma (Nirgude and Choudhary, 2021)

2001;42:225 [Google Scholar] 139.Liu Y., Borchert G.L., Surazynski A., Hu C.A., Phang J.M

Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria

Prevention of oxidant-induced cell death by lysosomotropic iron chelators