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Notably, RBD patients with hyposmia had higher levels of SAA positivity, which was also higher than DAT positivity, suggesting that alpha-synuclein SAA becomes abnormal before DAT imaging 98

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doi: 10.1016/j.freeradbiomed.2009.01.004

In this section, we review evidence of the involvement of autophagy, endoplasmic reticulum stress, mitochondrial dysfunction, and macrophage polarization in UC pathology