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SE-EE promoted neuronal proliferation and neurogenesis by modulating CREB/BDNF signaling in scopolamine inflicted amnesic C57/BL6N mice Effects on CREB/BDNF protein expression in the hippocampus cAMP-response element binding protein (CREB) is a cellular transcription factor that has been reported to play major role in the activation of brain-derived neurotrophic factor (BDNF) gene, which aids in the enrichment of neuronal growth and protection

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Can ashwagandha help with anxiety and depression
2005 Jan;15(1):23-30
