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33 The increased muscle mass can counteract the weakness and fatigue experienced by fibromyalgia patients, reducing pain catastrophizing

While the metabolic evidence is limited to studies on rats,(1) what we do know is that B12 plays a major role in red blood cell production and formation, anemia prevention and healthy nervous system function

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Since competition exists between enteric pathogens and commensal microbes for B12 sequestering and sharing, we hypothesized that excessive cobalamin supplementation alters the gut microbiotas functional activity, creating a favorable environment for pathogen colonization and pathogenesis