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Both nicotinic acid and niacinamide are used in B3 deficiency and may also be helpful for depression, anxiety, and physical stress

doi: 10.1016/j.bbi.2012.02.008 424 BalinasCEaton-FitchNMaksoudRStainesDMarshall-GradisnikS

Increasing your vitamin B12 intake can protect against deficiency to prevent these side effects

Duration of treatment varies based on condition severity and individual response

Beyond sleep, researchers have studied DSIP for its effects on stress hormone regulation specifically its ability to modulate ACTH and cortisol secretion making it of interest in HPA axis research
