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Energy Metabolism in Astrocytes: High Rate of Oxidative Metabolism and Spatiotemporal Dependence on Glycolysis/Glycogenolysis. Journal of Cerebral Blood Flow and Metabolism 27: 219249

developed a novel [copper sulfide nanoparticle (CuS NP) + disulfiram prodrug (DQ) micelle + near infrared (NIR) laser](CDL) combination therapy

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The featured molecule, 13 , proved to be an XO inhibitor, and with an IC 50 value of 4.261 M, the compound was more potent than allopurinol, the drug used as a positive control with an IC 50 value of 4.678 M (Figure 7)

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