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Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models

IRP2 is a transcription factor sensitive to intracellular iron levels, modulating the expression of proteins related to iron and lipid metabolism, thus influencing cellular susceptibility to ferroptosis (36)

The ferroptosis inducer erastin irreversibly inhibits system x(c)- and synergizes with cisplatin to increase cisplatins cytotoxicity in cancer cells

Hyperphosphorylation of -syn at ser129 is an important step in the transformation of -syn both from soluble monomers to insoluble aggregates and from a non-toxic to a toxic form
