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Salmeterol Efficacy and Bias in the Activation and Kinase-Mediated Desensitization of beta2-Adrenergic Receptors

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In a study, activated protein C was shown to regulate the Bax/Bcl-2 ratio by inhibiting the tumor suppressor protein p53 and preventing apoptosis in hypoxic human brain endothelium by reducing caspase-3 signaling [114]

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