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Total flavonoids of Astragalus membranaceus protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice by inhibiting ferroptosis through SLC7A11/GPX-4 signaling pathway

however, these changes were reversed by ferroptosis activation (Fig

249,251 Dyslipidemia also affects Schwann cells, leading to mitochondrial dysfunction, endoplasmic reticulum stress, and oxidative stress, ultimately causing cell death

Around 40% of the participants were also using an SLG2 inhibitor before the trial began

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