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Recent studies have combined formulation optimisation with 3D-printed nasal cavity models, nasal casts, and related in vitro or ex vivo tools to quantify how formulation properties affect regional deposition and brain delivery (Maaz et al., 2021

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RhGH-mediated increase in IGFBP3, IGFBP5 and ALS results in increased ternary complexes and correlates positively with the increment in height SDS [31]
Proceedings of the International Congress of Myology

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