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doi: 10.1128/jb.00969-07 18 ChengY.ChengH.JiangC.QiuX.WangK.HuanW.et al

Histone lactylation as a driver of metabolic reprogramming and immune evasion

These findings suggest that NAC should be used at a dose 1200 mg/day to prevent exacerbations in patients with a chronic bronchitis phenotype of COPD and airway obstruction, while regular doses (600 mg/day) may be sufficient in the absence of airway obstruction [37]

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