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Methodology for Literature Search This review synthesized data from published articles ranging from 2017 to the present, along with five additional articles published between 2011 and 2016, to ensure a comprehensive analysis of the content
To enable nanoparticles to cross the BBB and reach the CNS specific targeting is needed [21, 25]
Shin DS, Zaretsky JM, Escuin-Ordinas H, Garcia-Diaz A, Hu-Lieskovan S, Kalbasi A, et al
doi: 10.1016/j.postharvbio.2019.110930 63
Clinical experience and limited human data suggest daily doses between 200-1000 g, with 500 g representing a commonly reported effective dose, though these figures lack rigorous clinical trial validation
