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Looking forward, several key research directions warrant urgent investigation: Spatiotemporal Dynamics of mtDNA Damage: Future studies should move beyond bulk tissue to map cell-type specific mtDNA mutations (e.g., exhausted CD8+ T cells vs

Appropriate laboratory practices should be followed to ensure safe handling, storage, documentation, and disposal
A coronary artery calcium test is a low-dose CT scan that measures calcified plaque in the coronary arteries

doi: 10.3390/genes8040113 7 EppSChuahSMHalaszM
