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The levels of proinflammatory cytokines (TNF- and Interleukin-6 (IL-6)), malonaldehyde (MDA), and oxidative stress factors (GSH and ROS) in the liver were determined using the corresponding ELISA kit from Jiangsu Mei Biao Biological Technology Co., Ltd

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The clinical manifestations of HH include to various degrees, hepatomegaly, cirrhosis, hepatocellular carcinoma, diabetes mellitus, hypogonadotrophic hypogonadism, impotence, hypothyroidism, restrictive cardiomyopathy, arrhythmias, heart failure, destructive arthropathy and hyperpigmentation