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Since there are only 4 interchain disulfide bridges in an IgG1, there are only 8 possible conjugation sites, thus conjugation via cysteine generates markedly lower heterogeneity compared to lysine-based conjugation and produces a mixture composed of even-numbered cytotoxin-loaded species as depicted in Panel B of Fig
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Mater (Basel)
miR-27a Regulates Endothelial Differentiation of Breast Cancer Stem like Cells
Proc Biochem 42:454458
