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Iron response element binding protein 2 (IREB2) boosts FTL and FTH1 expression, thereby inhibiting erastin-induced ferroptosis (23)

This entails a progressive decline in the ability to manage levels of oxidative damage, which results in changes to cellular proteins, lipids and nucleic acids (Reference Bansal and Kaushal2)

Mol Neurodegener (2007) 2(1):1

Carhart-Harris RL, Erritzoe D, Williams T, Stone JM, Reed LJ, Colasanti A, et al

DAO deficiency (Dao/ mice) increased susceptibility to BLM-induced fibrosis, likely due to D-amino acid accumulation disrupting metabolism, immune signaling, and epithelial homeostasis [129]