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Table 2 summarized some of the clinical studies reported in the literature highlighting the clinical effectiveness of polyphenols in patients with CFS

Kidney distress: Creatine is one of the most researched and safe options for healthy individuals when taken in the correct dosage
10.1007/s40265-023-01874-9 83 LeprettiM.MartuccielloS.Burgos AcevesM

doi: 10.1146/annurev-physiol-021115-105045

On the contrary, it's effect is felt most when it's lacking