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Additionally, patient-derived cell lines lack an external environment to study new interactions between the tumor cells and a non-native microenvironment

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2 mM NaF, and 1 mM dithiothreitol)

It is worth testing whether such an approach would involve a simpler surgical procedure compared with targeting subcortical nuclei, with less invasiveness, while offering the potential for long-term control of motor symptoms akin to DBS
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