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[20] Disclosure of Invention Technical Problem [21] As a result of extensive investigations with the purpose of solving the above- described problems, the inventors of the present invention have prepared acetyl L- carnitine hydrochloride by sequentially synthesizing 4-chloro-3-hydroxybutyronitrile (Korean Patent Application No

Incoming stress signals to the PVN of the hypothalamus through a wide range of humoral and neural pathways are caused by different factors including infections, pain, emotional distress, and cardiovascular changes due to physical activity [3]

10.1016/j.jacc.2019.11.060 18

Taken together, available inconclusive results put forward that high-quality and long-term randomized trials are still required to fully elucidate the clinical value of L-carnitine administration in these patients

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