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In one study, selegiline-loaded TC nanoparticles administered intranasally significantly improved behavioral markers of depression and restored mitochondrial function in rodent models, outperforming unmodified chitosan formulations

Similarly, mineral-coated NGF and GDNF were administered to rats with sciatic nerve injuries that significantly increased axonal growth and function, starting from the 7th week and continuing until the 12th week of administration [24]

Cell 29 , 6980 (2008)

The findings of this research provide a significant foundation for additional investigation into the pathogenesis and treatment of PD
