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Discuss with your prescriber before modifying the standard weekly schedule
Comment: Some commenters also asked CMS to consider how the measure may lead to bias

Your clinician may want to recheck your plan if bleeding changes, sleep worsens, or symptoms do not improve

Additionally, Dihexa has been shown to increase the production of neurotrophic factors, such as brain-derived neurotrophic factor (BDNF), which play a crucial role in promoting neuronal survival and growth

The loading phase of TB-500 protocols requires higher initial doses, which increases first-month costs compared to maintenance phases