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doi: 10.1016/j.jinorgbio.2011.08.028
and (5) it releases neurotransmitters to modulate neurogenesis [121]
C4H: Cinnamate-4-hydroxylase
Meulenbelt, I
Irinotecan can be activated by carboxylesterase 1/2 (CES1/2) and catalyzed to a more active metabolite SN-38, both of which could form an inhibitory complex with TOP1 and DNA (Takano and Sugiyama, 2017)
