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Significant differences compared to MCF7-GSTP1 membranes are indicated with **** p 0.0001, (one-way ANOVA with Dunnett multiple comparisons test)

RTA-408 protects kidney from ischemia-reperfusion injury in mice via activating Nrf2 and downstream GSH biosynthesis gene

Maintains healthy lipid metabolism and oxidative status

For this, we introduced a second copy of gspD under the control of the copper-inducible promoter, P cuoA at the attB site 75 into our clones that had successfully integrated the deletion plasmid