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Efficacy and safety of LY3298176, a novel dual GIP and GLP1 receptor agonist, in patients with type 2 diabetes: a randomised, placebocontrolled and active comparatorcontrolled phase 2 trial

Moderate-quality evidence (based upon 2400 patients throughout 34 trials and 47 various exercise interventions) has demonstrated that aerobic exercise can decrease pain intensity, enhance physical function, and reduce the severity of fatigue

Given the Rab GEF activity of CCZ-1 and the homology of Rab32 family members with Rab7, CCZ-1 might function with a different protein to activate and localize GLO-1

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Edwards JD, Hauser RA, O''Connor ML, Valds EG, Zesiewicz TA, Uc EY