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Furthermore, GSH supplementation has been shown to protect HIV patients from a variety of opportunistic diseases by (i) mitigating oxidative stress and chronic inflammation in HIV-associated neurodegenerative diseases, (ii) improving Th17 responses in HIV patients who have impaired gut mucosal defenses, and (iii) restoring Th1 responses to protect patients from TB coinfection

Mast cells are immune sentinels that release inflammatory mediators, such as histamine and cytokines, in response to perceived threats

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PMID 22872058

an Evelyn Trust Grant Project ref 24/08 Med-24-2313 (L.P.-J.)