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The Journal of clinical investigation

Preclinical research demonstrated that NNMT inhibition with 5-Amino-1MQ reduced white adipose tissue mass by ~35% , shrank adipocyte size by 30-40%, and lowered plasma cholesterol by ~30% all without affecting food intake

While the reaction is normal, signifying an active immune system, the resultant arm pain can range from a mild, barely noticeable discomfort to a more pronounced and debilitating experience for some individuals