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In vitro studies showed -tocopheryl phosphate and -tocopheryl succinate (two forms of -tocopherol supplementation) inhibited GSTO1 activity in a concentration-dependent manner [206,208]

The tradeoff is slightly less precision at the lowest titration doses, though the difference is clinically negligible

The resistance of malignancies and cancer-derived cell lines to specific chemo- and radiotherapies has been linked to high Prx levels

Human studies, while smaller in scale, support both efficacy and safety over extended periods