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When histamine accumulates in the body, it can lead to a range of symptoms, including: Headaches and migraines Digestive issues (bloating, diarrhea, stomach pain) Skin problems (itching, rashes, hives) Respiratory symptoms (nasal congestion, asthma-like symptoms) Anxiety and mood changes It's important to note that histamine intolerance can be challenging to diagnose, as its symptoms can mimic those of other conditions, such as food allergies or digestive disorders

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Authors' contributions HS, HSW and HR jointly designed the study and wrote the paper, and HS performed the research