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As such, diagnosis presents a complex challenge for physicians, while the lived experience for patients is one marked by uncertainty and often illness invalidation

549 The reactive astrocytes can promote excitotoxic injury of motor neurons by producing nitric oxide and peroxynitrite, which cause mitochondrial damage and apoptosis in cultured neurons, decreasing glutamate transport, releasing pro-apoptotic mediators selectively toxic to motor neurons

But if you have a diet that's chronically deficient in this essential nutrient, you may develop a range of unpleasant symptoms

It begins in the ear with the tympanic membrane and the cochlea, where the sound is transmitted and transformed into electrical energy for the brain to perceive

This is why assessment and professional advice are important before booking treatment