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Description
Peripheral opioid receptors, particularly upregulated during inflammation [59], offer a rationale for topical application in wounds, providing localized analgesia with a minimum systemic exposure
It is pertinent to point out here that Robinson and Smyth had reported dopachrome as one of the products of the oxidation of L-tyrosine catalysed by the enzyme tyrosinase 27
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These neurotrophic effects support neuronal survival, synaptic plasticity, and cognitive function maintenance during aging
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