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The augmented activities of AsA-GSH cycle enzymes (ascorbate peroxidase, glutathione reductase, and dehydroascorbate reductase) were unable to counteract these toxic effects

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The latter allows LPS to reach hepatic TLRs activating and further enhancing oxidative, inflammatory, and fibrogenetic mechanisms (75, 90, 91, 9194)

doi: 10.1002/hep.21280 47 BrownKSacksSHWongW

Rotenone, an environmental toxin, causes abnormal methylation of the mouse brain organoid's genome and ferroptosis