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Calvo SE, Tucker EJ, Compton AG et al (2010) High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency

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Therefore, we hypothesize that loss of intestinal barrier function is necessary to develop autoimmunity.(18) TH-1 and TH-2 Polar Shifts The immune system has two major immune responses: T-helper-1 (TH-1) response, which is mediated by T-cells T-helper-2 (TH-2) response, which is mediated by B-cells Both immune responses are important for protecting the body against foreign microbes and invaders

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