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Rudjer Boskovic Institute, Department of Molecular Medicine, Zagreb 10000, Croatia

Kynurenine signaling through the Aryl hydrocarbon receptor: implications for aging and healthspan
doi: 10.4103/pigmentinternational.pigmentinternational_29_21 81 PeiJPanXWeiGHuaY

The main difference is bioavailability at the target tissue

37,38 The basic structures of BMAL1, CLOCK, HIF-1, and HIF-1 all consist of: the bHLH domain that binds to DNA, the PAS domain that performs dimerization function, and the transactivation domains (TADs), and the corresponding domains between each molecule are similar (Fig
