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In addition, adipocytes release metabolic hormones such as leptin and adiponectin, known as adipokines
doi: 10.1034/j.1399-3054.2001.1110404.x
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Additionally, increased ChaC2 expression targets the Cadherin 1 gene (encoding E-cadherin) mutation, resulting in E-cadherin loss, increased epithelial-mesenchymal transformation and lymph node metastasis, ultimately contributing to the low differentiation of breast cancer (50)
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