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Although extensive research has focused on Ashwagandha root, the plants leaves are also abundant in withanolides, notably withaferin A, a compound recognized for its robust immunomodulatory and anti-inflammatory properties

Duan X, Zhang T, Feng L, de Silva N, Greenspun B, Wang X, et al

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A 2024 critical review noted that unexpectedly high B12 levels can be further investigated by a clinician if needed, preferably by directly measuring the carrier proteins haptocorrin and transcobalamin rather than relying on the commonly ordered PEG precipitation test, which the authors found nonspecific and potentially misleading (Fedosov, 2024)

Mechanisms of tau self-aggregation and neurotoxicity