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Description
EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD

Cholinergic agents (e.g., neostigmine)
doi: 10.3389/fnmol.2019.00204 16

This would mean that each SC sequesters its own subpopulation of the mobile electron carriers (CoQ and/or cytochrome c ) and electron transfer between two sequential enzymes (CI-CIII and CIII-CIV) occurs by successive reduction and reoxidation of the mobile intermediates that are enclosed in internal channels connecting one enzyme active site to another (50, 61)

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